Thomas HESTERKAMP: search on Z-Library

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1

Discovery of a Novel Hsp90 Inhibitor by Fragment Linking

Dr. John J. Barker, Dr. Oliver Barker, Dr. Stephen M. Courtney, Dr. Mihaly Gardiner, Dr. Thomas Hesterkamp, Dr. Osamu Ichihara, Dr. Owen Mather, Dr. Christian A. G. N. Montalbetti, Dr. Annett Müller,

Journal:

Year:

2010

Language:

english

File:

PDF, 606 KB

english, 2010

2

Fragment-based discovery and optimization of BACE1 inhibitors

James Madden, Jenny R. Dod, Robert Godemann, Joachim Kraemer, Myron Smith, Marion Biniszkiewicz, David J. Hallett, John Barker, Jane D. Dyekjaer, Thomas Hesterkamp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 710 KB

english, 2010

3

Fragment-based activity space: smaller is better

Thomas Hesterkamp, Mark Whittaker

Journal:

Current Opinion in Chemical Biology

Year:

2008

Language:

english

File:

PDF, 876 KB

english, 2008

4

High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand

Robert Cheng, Brunella Felicetti, Shilpa Palan, Ian Toogood-Johnson, Christoph Scheich, John Barker, Mark Whittaker, Thomas Hesterkamp

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

5

The multiple roles of computational chemistry in fragment-based drug design

Richard Law, Oliver Barker, John J. Barker, Thomas Hesterkamp, Robert Godemann, Ole Andersen, Tara Fryatt, Steve Courtney, Dave Hallett, Mark Whittaker

Journal:

Journal of Computer-Aided Molecular Design

Year:

2009

Language:

english

File:

PDF, 957 KB

english, 2009

6

Growing up in a dangerous environment: a network of multiple targeting and folding pathways for nascent polypeptides in the cytosol

Bernd Bukau, Thomas Hesterkamp, Joen Luirink

Journal:

Trends in Cell Biology

Year:

1996

Language:

english

File:

PDF, 3.75 MB

english, 1996

7

The actin monomers in the ternary gelsolin: 2 actin complex are in an antiparallel orientation

Thomas HESTERKAMP, Alan G. WEEDS, Hans Georg MANNHERZ

Journal:

Year:

1993

Language:

english

File:

PDF, 1.20 MB

english, 1993

8

Substrate Shuttling Between the DnaK and GroEL Systems Indicates a Chaperone Network Promoting Protein Folding

Alexander Buchberger, Hartwig Schröder, Thomas Hesterkamp, Hans-Joachim Schönfeld, Bernd Bukau

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 89 KB

english, 1996

9

Functional characterisation of serum DNase I in MRL-lprlpr mice

Manuel C. Peitsch, Thomas Hesterkamp, Bernhard Polzar, Hans Georg Mannherz, Jürg Tschopp

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.08 MB

english, 1992

10

Identification of the prolyl isomerase domain of Escherichia coli trigger factor

Thomas Hesterkamp, Bernd Bukau

Journal:

Year:

1996

Language:

english

File:

PDF, 623 KB

english, 1996

11

The Escherichia coli trigger factor

Thomas Hesterkamp, Bernd Bukau

Journal:

Year:

1996

Language:

english

File:

PDF, 299 KB

english, 1996

12

The impact of physical based methods screening and their delivery of better quality hits

Jan Kahmann, Dirk Winkler, Thomas Hesterkamp

Journal:

Drug Discovery Today: Technologies

Year:

2008

Language:

english

File:

PDF, 573 KB

english, 2008

13

Fragments: past, present and future

Mark Whittaker, Richard J. Law, Osamu Ichihara, Thomas Hesterkamp, David Hallett

Journal:

Drug Discovery Today: Technologies

Year:

2010

Language:

english

File:

PDF, 622 KB

english, 2010

14

Fragment screening by biochemical assay

Barker, John, Courtney, Steve, Hesterkamp, Thomas, Ullmann, Dirk, Whittaker, Mark

Journal:

Expert Opinion on Drug Discovery

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

15

Escherichia coli Trigger Factor is a Prolyl isomerase that Associates with Nascent Polypeptide Chains

Thomas Hesterkamp, Stefanie Hauser, Henrich Lütcke and Bernd Bukau

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

16

Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays

Godemann, Robert, Madden, James, Krämer, Joachim, Smith, Myron, Fritz, Ulrike, Hesterkamp, Thomas, Barker, John, Höppner, Sabine, Hallett, David, Cesura, Andrea, Ebneth, Andreas, Kemp, John

Journal:

Year:

2009

Language:

english

File:

PDF, 3.71 MB

english, 2009

17

[Current Topics in Microbiology and Immunology] || Antibiotics Clinical Development and Pipeline

Hesterkamp, Thomas

Year:

2015

Language:

english

File:

PDF, 320 KB

english, 2015

18

Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial

Koch, Till, Dahlke, Christine, Fathi, Anahita, Kupke, Alexandra, KrÃ¤hling, Verena, Okba, Nisreen M A, Halwe, Sandro, Rohde, Cornelius, Eickmann, Markus, Volz, Asisa, Hesterkamp, Thomas, Jambrecina, A

Journal:

The Lancet Infectious Diseases

Year:

2020

File:

PDF, 1.39 MB

2020